Searchable abstracts of presentations at key conferences in endocrinology

ea0049nsa5.1 | (1) | ECE2017

Methodical tools for the structural elucidation of G-protein coupled receptors

Scheerer Patrick

In my short methodological talk, I will present why we need a detailed structural description of membrane proteins such as the TSH receptors (TSHR) of the endocrine system and how can we succeed to get three-dimensional structures. The talk includes a methodical toolbox of protein-production or -stabilization and advanced structural biology techniques like protein X-ray crystallography and cryo-electron microscopy for selected examples....